DHT and Hair Loss: What You Should Know

What exactly is DHT?

Male pattern baldness, also known as androgenic alopecia, is one of the most prevalent causes of hair loss in men as they age. Women may suffer from this sort of hair loss as well, although it is considerably less prevalent. This type of hair loss affects approximately 30 million women in the United States, compared to 50 million men.

The body’s sex hormones are thought to be the most important underlying element in male pattern hair loss. DHT (dihydrotestosterone) is an androgen. An androgen is a sex hormone that contributes to the development of “masculine” sex traits such as body hair. However, it might cause you to lose your hair more quickly and prematurely. There are medications available that are designed to delay the development of male pattern baldness by particularly targeting DHT. Let’s talk about how DHT works, how it affects your hair and testosterone, and what you can do to prevent or postpone male pattern baldness.

DHT Causes | Hair Loss | Dihydrotestosterone - Tentaran

What is the function of DHT?

DHT is a byproduct of testosterone. Testosterone is a hormone found in both males and women. It and DHT are androgens, which are hormones that contribute to male sex characteristics throughout puberty. These characteristics are as follows:

  • a deep tone of voice
  • increased muscle mass and body hair
  • As sperm production starts, the penis, scrotum, and testicles enlarge.
  • alterations in the way fat are stored in your body

As you age, testosterone and DHT provide several additional advantages to your body, such as preserving total muscle mass and improving sexual health and fertility. Men often have higher levels of testosterone in their bodies. With the aid of an enzyme called 5-alpha reductase, about 10% of testosterone in all individuals is transformed to DHT (5-AR). DHT may then bind to receptors on hair follicles in your scalp, causing them to shrink and become less capable of sustaining a healthy head of hair once it’s freely circulating through your circulation. DHT’s potential for damage extends beyond your hair. DHT, particularly extremely high amounts of it, has been associated to:

  • Skin recovery after an injury is gradual.
  • prostate enlargement
  • cancer of the prostate
  • coronary artery disease

Having insufficient DHT

High DHT levels may put you at risk for certain illnesses, but having too little DHT can potentially create difficulties with your sexual development throughout puberty. Low DHT levels may induce puberty delays in both sexes. Otherwise, low DHT seems to have no impact on women, while in males, low DHT may cause:

  • The development of genital organs such as the penis or testes is delayed or incomplete.
  • alterations in the distribution of body fat, resulting in situations such as gynecomastia
  • an increase in the likelihood of developing aggressive prostate tumors

Why do individuals react differently to DHT?

Your predisposition for hair loss is hereditary, which means it has been handed down through your family. For example, if you’re a man and your father has male pattern baldness, you’re likely to have a similar balding pattern as you age. If you are predisposed to male pattern baldness, DHT’s follicle-shrinking action is more prominent. DHT’s ability to decrease your follicles may also be affected by the size and shape of your head.

Hair Care with Essential Oils

The link between DHT and baldness

Hair develops from structures under your skin called follicles, which are basically small capsules that each contain a single strand of hair. A follicle’s hair normally goes through a growth cycle that lasts two to six years. Even if you shave or cut your hair, the same hair will regrow from the root of the hair trapped inside the follicle. The hair enters a resting phase at the conclusion of this cycle before eventually falling out a few months later.

The follicle then grows a new hair, and the cycle starts again. High amounts of androgens, particularly DHT, may decrease your hair follicles and shorten this cycle, causing hair to come out thinner and brittle, as well as fall out quicker. DHT may also cause your follicles to take longer to regenerate new hairs once old hairs fall out.


Variations in the androgen receptor (AR) gene make certain persons more vulnerable to the effects of DHT on scalp hair. Androgen receptors are proteins that bind to hormones such as testosterone and DHT. This binding activity is often associated with normal hormonal activities such as body hair development. Variations in the AR gene, on the other hand, might enhance androgen sensitivity in your scalp follicles, increasing your chances of experiencing male pattern hair loss.

Testosterone vs. DHT

The most abundant and active androgen in the male body is testosterone. It is in charge of a variety of sexual and physiological functions, including:

  • controlling the amounts of androgen hormones throughout the body
  • controlling sperm production
  • maintaining muscle mass and bone density
  • assisting in the distribution of fat throughout the body
  • controlling your emotions and mood

DHT is a testosterone by-product. DHT, like testosterone, plays a part in some of the same sexual activities and physiological processes, although it is considerably stronger. DHT has the ability to attach to an androgen receptor for a longer period of time, boosting the influence of testosterone production throughout your body.

How to Lower DHT

There are several drugs available to treat DHT-related hair loss, and many of them have been shown to be effective by precisely targeting DHT synthesis and receptor binding. There are two major kinds:

Blockers. These block DHT from attaching to 5-AR receptors, particularly those in your hair follicles, where DHT may cause follicle shrinkage.

Inhibitors. These inhibit the formation of DHT in your body.


Finasteride (Proscar, Propecia) is a prescription-only drug that is taken orally. In one 2012 study on 3,177 males, it was shown to have at least an 87 percent success rate, with minor negative effects. Finasteride interacts with 5-AR proteins, preventing DHT from interacting with them. This prevents DHT from attaching to receptors on your hair follicles, causing them to shrink.


A peripheral vasodilator is minoxidil (Rogaine). This implies that it aids in the widening and loosening of blood arteries, allowing blood to flow more readily through them. It is often used to treat high blood pressure. However, when administered topically to your scalp, minoxidil may help increase hair growth.

What Causes Baldness in Men and What Can Be Done About It?


Biotin, often known as vitamin H, is a natural B vitamin that aids in the conversion of some of the food and liquids you ingest into energy that your body can utilize. Biotin also helps to increase and maintain keratin levels, which are found in your hair, nails, and skin. The research on why biotin is vital for your body’s keratin levels is inconclusive. However, according to 2015 research, biotin may help hair regenerate and protect current hair from falling out. Biotin may be taken orally, but it’s also found in egg yolks, almonds, and healthy grains.

Pygeum bark

Pygeum is a plant-derived from the bark of the African cherry tree. It is often offered as an oral herbal supplement. Because of its DHT-blocking properties, it is widely recognized as a potentially useful therapy for an enlarged prostate and prostatitis. As a result, it’s regarded to be a potential therapy for DHT-related hair loss. However, there is very little evidence to support the use of pygeum bark alone as an effective DHT blocker.

Pumpkin seed oil

Another DHT blocker that has been demonstrated to be effective is pumpkin seed oil. A 2014 study of 76 individuals with male pattern baldness found that ingesting 400 mg of pumpkin seed oil every day for 24 weeks resulted in a 40% rise in average scalp hair count.


There has been very little study on whether caffeine may enhance hair growth. However, according to a 2014 study, caffeine may help reduce hair loss by:

  • making your hair grow longer
  • lengthening the growing phase of hair
  • encouraging keratin production

B-12 and B-6 vitamins

Deficiencies in B vitamins, particularly B-6 and B-12, may result in a variety of symptoms, including thinning or loss of hair. While taking B-12 or B-6 pills will not help recover lost hair, they will help make your hair thicker and healthier by boosting blood flow to scalp follicles.

DHT blocker’s side effects

DHT blockers have been linked to the following adverse effects:

  • erection problems
  • ejaculating too soon or ejaculating too slowly
  • increased fat accumulation and soreness in the breast region
  • rash
  • feeling ill
  • vomiting
  • face and upper body hair darkening and thickening
  • congestive heart failure is caused by salt or water retention, which is more likely with minoxidil

Other reasons for hair loss

DHT isn’t the sole reason your hair is thinning or falling out. Here are a few more possible causes of hair loss.

Alopecia areata

Alopecia areata is an autoimmune disorder in which your body assaults the hair follicles on your head and elsewhere. Though you may notice minor patches of hair loss at first, this disorder may ultimately result in total baldness on your head, brows, facial hair, and body hair.

Lichen planus

Another autoimmune illness that causes your body to attack skin cells, including those on your scalp, is lichen planus. This might cause follicular damage, causing your hair to fall out.

Thyroid conditions

Conditions that cause your thyroid gland to produce too much (hyperthyroidism) or too little (hypothyroidism) of particular thyroid hormones that help regulate your metabolism might cause hair loss on your scalp.

Celiac disease

Celiac disease is an autoimmune disorder that causes intestinal dysfunction in reaction to gluten, a protein present in bread, oats, and other grains. Hair loss is one of the symptoms of this illness.

Scalp infections

Various scalp illnesses, particularly fungal infections such as tinea capitis (commonly known as ringworm of the scalp), may cause your scalp to become scaly and itchy, causing hair to fall out of affected follicles.

Bamboo hair

Bamboo hair occurs when the surfaces of your individual hair strands seem thin, knotty, and segmented rather than smooth. It’s a typical sign of Netherton syndrome, a hereditary illness that causes excessive skin shedding and abnormal hair growth.

In Conclusion

DHT is a well-known and significant cause of male pattern hair loss. It is connected to both your natural genetic propensity to hair loss and natural processes in your body that lead you to lose hair as you age. There are several DHT-related hair loss therapies available, and minimizing hair loss may help you feel more confident about your look in daily life. However, consult with a doctor first since not all therapies are safe or beneficial for you.

Check Out More At @usahealthline

Latest news

Related news


Please enter your comment!
Please enter your name here